Does The Use Of Salvia Divinorum Prolong The Blood Clotting Time?

Interaction Between warfarin and Danshen (sage miltiorrhizaBy Chan TYK in Annals of Pharmacotherapy Vol .35 , pp . 501-504This glossiness is an attempt to substantiate the traditionalistic hold of the salvia miltiorrhiza flora , comm precisely known as dan shen , in eliminating riptide stasis and enhancing manikin circulation as indicated by traditional Chinese Medicine . The Chinese go for long utilize it to accelerate menstrual neckcloth flow and is withal positivist to patients with cardiovascular diseases as advantageously as other ailmentsConducted in 2001 , Chan s work foc determinationd on the interaction of these two substances in reality . He reviewed the cases of trey patients who were taking long margin warfarin treatments and then took Salvia miltiorrhiza (commonly known as dan shen ) aft(prenominal) some time . They arriveed from anticoagulant medication medication dose with riotous bleeding that led to complications . Dan shen was place as the cause of the overdose in the said cases because in that location were no other components to which it could be attri besidesed toAs scientific grounds on dan shen s rear on rootage clotting time is shy(predicate) , this theatre adds to the current association on this aspect It alike points to the potentials of the herb for the development of an election anti-coagulant especi ally for patients suffering from cerebrovascular accident and the accompanying blood clotting in the brain . shortly , ceremonious Western medicines urge on so far proven sufficient for effective treatmentsThere argon limitations in the study . Because it only reviewed tether cases of warfarin and dan shen use with bleeding complications , the sample would non search to be substitute of all the cases involving the use of both substances . come on , the tec failed to ascertain the dosages of dan shen taken by the patients as hale as the severity of overdose designate on the dosages ingested that would dish live with a fit the burdens of the studyAlso , subjecting the dan shen substances to chemical analysis so as to discriminate its discordant components and identify which slows down factor II bodily process would grow been beneficial to the study . It may alike be executable that the warfarin medication apply did not act the mountain up standard for the represent of the drug for it to cause wayward array effects but in assuming that it did meet standards , warfarin was eliminated as a factor in itselfThe drawn-out use of the medicine , as was the case in the patients could also have predisposed them to suffer from excessive bleeding . The differences in the lengths of warfarin treatment should also have been considered as a factor .

hitherto , it does heed physicians against allowing patients to take both warfarin and on the fence(p) amounts of dan shenWhen seen in simile to the overall effort of establishing the anticoagulant exertion of dan shen in humans , this study would only establish the fortune for such(prenominal) properties because it is presumed to have caused the said overdose . However , it does not conclusively go steady that the intake of the herb does impart in such activity in humans such that when unite with drugs with the selfsame(prenominal) properties , it would result in anti-coagulant overdoseMore compelling evidence croup be naturalized for both the interaction of warfarin and dan shen if a double-blind study were to be conducted involving randomly selected participants divided into maintain and placebo groups . geminate blind studies be also necessary to think on its anti-coagulant property and in to be reliableBecause dan shen has been traditionally established as an anticoagulant , a non-double-blind study would result in many a(prenominal) possible biases that slur the conclusions . It should also be replicated to go down if all studies reach the same conclusions . In vitro studies involving dan shen treatment or the crew of dan shen and warfarin argon also essentialList of ReferencesOliff , H .S (2001 . Chinese herb Danshen Interacts with Warfarin causing Longer Bleeding period . Retreived 4 April 2008 from http / vane .physiologics .com /herbclip /review .asp ?i 42690 PAGEPAGE 3 ...If you involve to get a full essay, order it on our website: Orderessay

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